Research Associate/ Fellow (Fixed Term)
University of Nottingham – Veterinary Medicine & Science · United Kingdom
Postdoctoral Research Fellow position in molecular biology at University of Nottingham, focused on developing plasma extracellular vesicle RNA biomarkers to improve diagnosis of Dementia with Lewy bodies. The role involves RNA sequencing analysis and AI-based analytical approaches, working within a multidisciplinary research team.
This opportunity has closed.
About this opportunity
per annum, depending on skills and experience (minimum £35608 with relevant PhD).
We are seeking a highly motivated and enthusiastic Postdoctoral Research Fellow to join the molecular biology group led by Professor Victoria James at the University of Nottingham. This exciting position is funded by an Alzheimer's Research UK (ARUK) project awarded to Clinical Lead Dr Anto Rajamani and offers an opportunity to contribute to cutting-edge research aimed at improving the diagnosis of Dementia with Lewy bodies (DLB).
The successful candidate will deliver the experimental research focused on improving the diagnostic accuracy of a multiplex plasma extracellular vesicle (EV) RNA biomarker assay for DLB. This work has the potential to advance earlier and more accurate diagnosis of one of the most challenging neurodegenerative diseases.
The postholder will lead the generation and analysis of next-generation RNA sequencing (RNA-seq) data from patient-derived extracellular vesicle samples to identify DLB-specific RNA signatures. They will also support the implementation and evaluation of artificial intelligence (AI)-based analytical approaches to improve the sensitivity and specificity of biomarker-based diagnosis.
Working within a multidisciplinary and collaborative environment, you will work closely with our clinical lead, Dr Anto Rajamani, members of the molecular biology laboratory, PhD students, bioinformatics collaborators, and other clinical partners.
This position provides an outstanding opportunity to contribute to translational research with real potential to improve patient diagnosis and care. You will join a supportive and collaborative research environment within the University of Nottingham and work alongside leading researchers in molecular biology, clinical neurology, biomarker discovery, and computational analysis. You will play an important role in driving the project forward while contributing to the development of an inclusive, supportive, and collaborative research culture.
We are committed to fostering equality, diversity, and inclusion and welcome applications from candidates from all backgrounds. Flexible working arrangements and opportunities for career development are supported wherever possible.
If you are passionate about translational neuroscience, biomarker discovery, and applying innovative molecular and computational approaches to improve dementia diagnosis, we would be delighted to hear from you.
Further information is available in the role profile. This position is a fixed-term contract for 30 months. To apply for this vacancy please click ‘Apply Now’ to complete your details and upload a copy of your CV.
Please contact Professor Victoria James ( Victoria.james@nottingham.ac.uk ) and Dr Anto Rajamani ( Anto.Rajamani@nottingham.ac.uk ) if you have further questions about this role. Please note that we will be unable to accept applications sent directly by email.
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Eligibility
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Academic requirements
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English language requirements
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How to apply
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